Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | PTGFR | P43088 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372892 | 0.91 | DHODH (0.44) | DHODHPDE10APTGFRMAPT | |
| SCHEMBL2372981 | 0.86 | DHODH (0.56) | DHODHPDE10APTGFRTSHR | |
| SCHEMBL2373164 | 0.86 | DHODH (0.56) | DHODHPDE10APTGFRTSHR | |
| SCHEMBL2462422 | 0.84 | DHODH (0.53) | DHODHPDE10APTGFRTSHR | |
| SCHEMBL2372825 | 0.83 | DHODH (0.64) | DHODHPDE10APTGFRTSHR | |
| SCHEMBL2372311 | 0.83 | TRPV4 (0.40) | DHODHPTGFRMAPT | |
| SCHEMBL2372552 | 0.82 | DHODH (0.62) | DHODHPDE10APTGFRTSHR | |
| SCHEMBL2372628 | 0.82 | DHODH (0.47) | DHODHPTGFR | |
| SCHEMBL2373266 | 0.82 | DHODH (0.47) | DHODHPDE10APTGFRMAPT | |
| SCHEMBL2372758 | 0.82 | DHODH (0.56) | DHODHPDE10APTGFRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |