SCHEMBL23728965

SCHEMBL23728965

Oc1ccc(Cl)cc1-c1ccc2c(c1)c1cccc3c1n2c1cccc2c4ccccc4n3c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
HPGD P15428 3/20 0.40
HTT P42858 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 2/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PIM1 P11309 1/20 0.38
ALOX5 P09917 1/20 0.35
RXFP1 Q9HBX9 2/20 0.34
TP53 P04637 1/20 0.34
DNM1 Q05193 1/20 0.34
IDO1 P14902 3/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723201 0.82 MAPT (0.46) MAPTMEN1KMT2AHPGDHTT
SCHEMBL19387982 0.77 MAPT (0.49) MAPTMEN1KMT2AHPGDHTT
SCHEMBL16621739 0.74 KDM4E (0.44) MAPTMEN1KMT2AHPGDHTT
SCHEMBL10153530 0.74 KDM4E (0.44) MAPTMEN1KMT2AHPGDHTT
SCHEMBL26447068 0.74 MAPT (0.43) MAPTMEN1KMT2AHPGDHTT
SCHEMBL23814251 0.73 KDM4E (0.39) MAPTMEN1KMT2AHPGDHTT
SCHEMBL15434826 0.73 TSPO (0.43) MAPTMEN1KMT2AHPGDHTT
SCHEMBL23728960 0.72 MAPT (0.39) MAPTMEN1KMT2AHPGDHTT
SCHEMBL21710469 0.72 KDM4E (0.38) MAPTMEN1KMT2AHPGDHTT
SCHEMBL26522757 0.71 MAOA (0.39) MAPTMEN1KMT2AHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021153931-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-08-05 WO disclosed