SCHEMBL23729173

SCHEMBL23729173

Ic1c(-c2ccc3ncn(-c4ccccc4)c3c2)cccc1-c1ccc2ncn(-c3ccccc3)c2c1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
FGFR1 P11362 9/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
MAPK1 P28482 1/20 0.54
MAPK10 P53779 1/20 0.54
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54
SRC P12931 2/20 0.51
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23729329 0.90 KDR (0.58) HTTFGFR1ALDH1A1SRC
SCHEMBL23729737 0.87 HTT (0.56) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL18910380 0.85 FGFR1 (0.50) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL23772771 0.83 HTT (0.52) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL16291053 0.83 HTT (0.62) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL15430813 0.79 FGFR1 (0.64) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL20698049 0.78 HTT (0.65) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL19228785 0.78 HTT (0.56) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL18609345 0.78 FGFR1 (0.56) HTTFGFR1ALDH1A1HPGDMAPK1
SCHEMBL16923444 0.77 HTT (0.54) HTTFGFR1ALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
EP-3858945-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed