SCHEMBL18910380

SCHEMBL18910380

c1ccc(-n2cnc3ccc(-c4cccc5c6ccccc6c6ccccc6c45)cc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 5/20 0.50
HTT P42858 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
MAPK10 P53779 1/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
ACVR1 Q04771 1/20 0.48
SRC P12931 2/20 0.48
PRKCI P41743 4/20 0.47
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23729173 0.85 HTT (0.54) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL23729737 0.83 HTT (0.56) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL19228785 0.83 HTT (0.56) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL23772771 0.80 HTT (0.52) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL19991628 0.80 PRKCI (0.41) HTTALDH1A1ACVR1PRKCIATM
SCHEMBL16291053 0.79 HTT (0.62) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL19820122 0.77 PRKCI (0.35) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL15430813 0.75 FGFR1 (0.64) FGFR1HTTALDH1A1HPGDMAPK1
SCHEMBL23729329 0.75 KDR (0.58) FGFR1HTTALDH1A1SRC
SCHEMBL18609345 0.74 FGFR1 (0.56) FGFR1HTTALDH1A1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11765966-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-20230192636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230117045-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-10 US disclosed
US-20220298190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
US-20220185826-A1 Tandem Carbene Phosphors THE UNIVERSITY OF SOUTHERN CALIFORNIA 2022-06-16 US disclosed
US-20220162243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-26 US disclosed
US-20220115601-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2022-04-14 US disclosed
US-20220009955-A1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2022-01-13 US disclosed
US-20210074934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-10862046-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-08 US disclosed
US-20200373510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-26 US disclosed
US-20200185625-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 US disclosed
US-10476010-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-11-12 US disclosed
US-10253252-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-04-09 US disclosed
US-10199582-B2 Organic electroluminescent materials and devices UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2019-02-05 US disclosed
US-9929353-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 US disclosed
US-20170155064-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009955-A1 Organic electroluminescent materials and devices CRKL, CNKSR1, SGK2 FGFR1 1418/4885HTT 3638/4885ALDH1A1 2444/4885
US-20220162243-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, LOXL1 FGFR1 3007/4885HTT 3814/4885ALDH1A1 75/4885
US-20210074934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 FGFR1 3472/4885HTT 3468/4885ALDH1A1 88/4885
US-20220185826-A1 Tandem Carbene Phosphors OCIAD1, CCND2, OCIAD2 FGFR1 1049/4885HTT 2920/4885ALDH1A1 1759/4885
US-20220298190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, LARP1 FGFR1 1665/4885HTT 3380/4885ALDH1A1 690/4885
US-20230192636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG FGFR1 2811/4885HTT 1861/4885ALDH1A1 142/4885
US-20220115601-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND FGFR1 3607/4885HTT 3887/4885ALDH1A1 400/4885
US-20200185625-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EML4 FGFR1 2815/4885HTT 1066/4885ALDH1A1 2220/4885
US-10253252-B2 Organic electroluminescent materials and devices LEF1, TYR, YBX1 FGFR1 1556/4885HTT 3641/4885ALDH1A1 1390/4885
US-10476010-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OPRD1 FGFR1 2457/4885HTT 2978/4885ALDH1A1 661/4885
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, EPM2A FGFR1 4054/4885HTT 4562/4885ALDH1A1 1028/4885
US-20230117045-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, CNKSR1, LOXL1 FGFR1 1815/4885HTT 4567/4885ALDH1A1 2809/4885
US-11765966-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, EPM2A FGFR1 4054/4885HTT 4562/4885ALDH1A1 1028/4885
US-20170155064-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND FGFR1 4017/4885HTT 622/4885ALDH1A1 1651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.