SCHEMBL23729329

SCHEMBL23729329

Ic1c(-c2ccc3c(c2)ncn3-c2ccccc2)cccc1-c1ccc2c(c1)ncn2-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDR P35968 1/20 0.58
HTT P42858 1/20 0.57
FGFR1 P11362 11/20 0.56
ALDH1A1 P00352 1/20 0.50
SRC P12931 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23729173 0.90 HTT (0.54) HTTFGFR1ALDH1A1SRC
SCHEMBL23772972 0.82 KDR (0.57) KDRHTTFGFR1ALDH1A1
SCHEMBL12135624 0.82 KDR (0.76) KDRHTTFGFR1ALDH1A1SRC
SCHEMBL26278653 0.78 KDR (0.62) KDRHTTFGFR1
SCHEMBL15430812 0.78 ALDH1A1 (0.64) KDRFGFR1ALDH1A1
SCHEMBL23266613 0.77 HTT (0.61) HTTFGFR1ALDH1A1
SCHEMBL23729737 0.77 HTT (0.56) KDRHTTFGFR1ALDH1A1SRC
SCHEMBL23099348 0.77 KDR (0.57) KDRHTTFGFR1ALDH1A1SRC
SCHEMBL20160441 0.77 KDR (0.64) KDRHTTFGFR1ALDH1A1SRC
SCHEMBL7677283 0.77 KDR (0.68) KDRHTTFGFR1ALDH1A1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
EP-3858945-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed