Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028575 | 0.91 | CYP2D6 (0.44) | DRD2TLR8ACKR3 | |
| SCHEMBL23705617 | 0.84 | ACACB (0.40) | DRD2TLR8GPR183ACACBSCD5 | |
| SCHEMBL29617085 | 0.84 | ACACB (0.40) | DRD2TLR8GPR183ACACBSCD5 | |
| SCHEMBL21997274 | 0.84 | ACKR3 (0.50) | TLR8ACKR3SIGMAR1 | |
| SCHEMBL24373884 | 0.80 | EPHX2 (0.39) | GPR183ACACBSCD5HDAC1HDAC2 | |
| SCHEMBL17946542 | 0.79 | SCD5 (0.45) | GPR183ACACBSCD5HDAC1HDAC2 | |
| SCHEMBL28891307 | 0.79 | CYP4F2 (0.41) | GPR183ACACBSCD5CYP11B2 | |
| SCHEMBL17946237 | 0.78 | ACACB (0.42) | GPR183ACACBSCD5HDAC1HDAC2 | |
| SCHEMBL23705741 | 0.78 | SIGMAR1 (0.52) | DRD2ACKR3SIGMAR1 | |
| SCHEMBL996002 | 0.77 | USP2 (0.46) | GPR183ACACBSCD5HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |