Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12934640 | 0.94 | TSHR (0.69) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL21947703 | 0.90 | TSHR (0.73) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL12840596 | 0.89 | TSHR (0.63) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL14262301 | 0.88 | TSHR (0.81) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL14561105 | 0.87 | TSHR (0.51) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL10345306 | 0.86 | NAMPT (0.52) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL10660707 | 0.86 | NAMPT (0.52) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL10345059 | 0.86 | NAMPT (0.52) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL24818366 | 0.86 | NAMPT (0.52) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL23787581 | 0.86 | TSHR (0.67) | TSHRHPGDMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |