Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090657 | 0.95 | TSHR (0.69) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12934640 | 0.95 | TSHR (0.69) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL4264199 | 0.95 | TSHR (0.69) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL23787581 | 0.94 | TSHR (0.67) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13483552 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL14065638 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL16728765 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13023957 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL12299083 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E | |
| SCHEMBL13423640 | 0.90 | TSHR (0.61) | TSHRHPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897143-B2 | Amphipathic amide lipid, anionic surfactant, and acid or salt; feel, moisture retention, smoothness, stability; shampoo | KAO CORPORATION (JP) | 2011-03-01 | — | — | US | disclosed |