Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26700763 | 1.00 | TSHR (0.42) | TSHRHPGDADRB2ADRB1CASP2 | |
| SCHEMBL26708617 | 1.00 | TSHR (0.42) | TSHRHPGDADRB2ADRB1CASP2 | |
| SCHEMBL26708616 | 0.98 | TSHR (0.44) | TSHRHPGDADRB2ADRB1CASP2 | |
| SCHEMBL23729313 | 0.87 | HPGD (0.46) | TSHRHPGDADRB2ADRB1CASP2 | |
| SCHEMBL23729791 | 0.87 | TSHR (0.44) | TSHRHPGDCASP2SMN1; SMN2FAAH | |
| SCHEMBL23730071 | 0.87 | SMN1; SMN2 (0.53) | TSHRHPGDCASP2SMN1; SMN2FAAH | |
| SCHEMBL23729612 | 0.85 | FAAH (0.43) | TSHRHPGDCASP2SMN1; SMN2FAAH | |
| SCHEMBL26708614 | 0.85 | FAAH (0.43) | TSHRHPGDCASP2SMN1; SMN2FAAH | |
| SCHEMBL23729617 | 0.85 | TSHR (0.45) | TSHRHPGDCASP2SMN1; SMN2FAAH | |
| SCHEMBL26700903 | 0.84 | FAAH (0.42) | TSHRHPGDCASP2SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | TSHR 4245/4885HPGD 3620/4885ADRB2 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.