Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26700763 | 0.87 | TSHR (0.42) | SMN1; SMN2CASP2TSHRNAAAFAAH | |
| SCHEMBL26708162 | 0.87 | TSHR (0.42) | SMN1; SMN2CASP2TSHRNAAAFAAH | |
| SCHEMBL26708617 | 0.87 | TSHR (0.42) | SMN1; SMN2CASP2TSHRNAAAFAAH | |
| SCHEMBL23729313 | 0.85 | HPGD (0.46) | SMN1; SMN2CASP2TSHRNAAAALDH1A1 | |
| SCHEMBL26708616 | 0.85 | TSHR (0.44) | SMN1; SMN2CASP2TSHRNAAAALDH1A1 | |
| SCHEMBL25835006 | 0.82 | TSHR (0.47) | SMN1; SMN2TSHREPHX2ALDH1A1FAAH | |
| SCHEMBL23729792 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2CASP2TSHREPHX2NAAA | |
| SCHEMBL20470166 | 0.81 | CASP2 (0.53) | CASP2EPHX2NAAAFAAHPRCP | |
| SCHEMBL29302109 | 0.81 | CASP2 (0.65) | CASP2EPHX2NAAAFAAHPRCP | |
| SCHEMBL29300290 | 0.81 | CASP2 (0.65) | CASP2EPHX2NAAAFAAHPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |