Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730060 | 0.91 | SMN1; SMN2 (0.60) | TSHRSMN1; SMN2CNR1ALDH1A1RAB9A | |
| SCHEMBL15888696 | 0.88 | TSHR (0.69) | TSHRSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL23729602 | 0.87 | TSHR (0.77) | TSHRSMN1; SMN2CNR1HPGDHTT | |
| SCHEMBL13492963 | 0.85 | SMN1; SMN2 (0.59) | TSHRSMN1; SMN2CNR1ALDH1A1RAB9A | |
| SCHEMBL19588529 | 0.85 | TSHR (0.69) | TSHRSMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL13501556 | 0.83 | CNR1 (0.67) | TSHRSMN1; SMN2CNR1HPGDHTT | |
| SCHEMBL23729787 | 0.82 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL7323180 | 0.81 | CNR1 (0.69) | TSHRSMN1; SMN2CNR1HPGDHTT | |
| SCHEMBL15888730 | 0.81 | TSHR (0.59) | TSHRSMN1; SMN2HPGDHTTMEN1 | |
| SCHEMBL23478140 | 0.80 | TSHR (0.65) | TSHRSMN1; SMN2CNR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |