SCHEMBL23729783

SCHEMBL23729783

COCCC1CN(C(=O)C2(C(C)C)CC2)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.31
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26700750 0.87 EPHX2 (0.31)
SCHEMBL26707903 0.84
SCHEMBL26700752 0.77 SLC1A3 (0.32)
SCHEMBL23716464 0.73 CHRNB2 (0.41) HSD11B1AKR1C3
SCHEMBL17190675 0.72 CHRNB2 (0.36) HSD11B1
SCHEMBL26700753 0.71
SCHEMBL26700771 0.70 KCNH2 (0.34)
SCHEMBL23716522 0.68 CHRNB2 (0.50) HSD11B1AKR1C3
SCHEMBL71823 0.67 NR1H2 (0.54)
SCHEMBL17190679 0.65 HSD11B1 (0.39) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155321-A2 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2021-08-05 WO disclosed