Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.40 |
| ▸ | PRKDC | P78527 | 13/20 | 0.40 |
| ▸ | MTOR | P42345 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730146 | 0.81 | HPD (0.47) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23730148 | 0.81 | PRKDC (0.48) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23729702 | 0.74 | HPD (0.43) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23730143 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPK1KDM4ETSHRHTT | |
| SCHEMBL23729671 | 0.72 | HPD (0.42) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23729674 | 0.71 | HPD (0.41) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23729675 | 0.71 | HPD (0.41) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23730136 | 0.71 | HPD (0.41) | HPDCRHBPCRHR2RXFP1PIK3CA | |
| SCHEMBL23730200 | 0.70 | HPD (0.41) | HPDPIK3CAALDH1A1 | |
| SCHEMBL10962187 | 0.68 | GSK3A (0.46) | HPDCRHBPCRHR2RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858818-A1 | TRIKETONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE | Shandong Cynda Chemical Co., LTD. (CN) | 2021-08-04 | — | — | EP | disclosed |