Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | BRD2 | P25440 | 2/20 | 0.52 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TPH2 | Q8IWU9 | 11/20 | 0.46 |
| ▸ | TPH1 | P17752 | 10/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19090311 | 0.94 | MEN1 (0.49) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL19090320 | 0.87 | ALDH1A1 (0.43) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL23731232 | 0.80 | ALDH1A1 (0.43) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389530 | 0.79 | BRD4 (0.56) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389561 | 0.79 | BRD4 (0.56) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389536 | 0.78 | BRD4 (0.57) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389578 | 0.74 | MEN1 (0.83) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389560 | 0.73 | MEN1 (0.51) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL21389579 | 0.73 | MEN1 (0.66) | BRD4BRD2BRD3MEN1KMT2A | |
| SCHEMBL19090312 | 0.72 | MEN1 (0.49) | BRD4BRD2BRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |