Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730987 | 0.68 | SMN1; SMN2 (0.38) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL11456944 | 0.66 | ABL1 (0.41) | SMN1; SMN2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL8726371 | 0.65 | KMT2A (0.54) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL1363146 | 0.63 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL11450210 | 0.62 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL11460411 | 0.62 | GAA (0.38) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL1361115 | 0.62 | MMP1 (0.46) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL4646184 | 0.62 | MMP1 (0.46) | SMN1; SMN2CYP19A1PTGS1PTGS2MGLL | |
| SCHEMBL9186739 | 0.62 | ALDH1A1 (0.44) | SMN1; SMN2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL11457589 | 0.61 | CDC25A (0.46) | SMN1; SMN2ABL1RIN1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |