Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255225 | 0.78 | GAA (0.33) | ABL1RIN1TDP1GAA | |
| SCHEMBL21389537 | 0.74 | ABL1 (0.35) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL21389532 | 0.72 | ABL1 (0.33) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL18466242 | 0.69 | GBA1 (0.38) | ABL1RIN1TDP1GAAGBA1 | |
| SCHEMBL21389575 | 0.64 | GAA (0.41) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL11024134 | 0.57 | GAA (0.46) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL6233301 | 0.57 | GAA (0.46) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL11371116 | 0.56 | GBA1 (0.58) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL6231243 | 0.53 | GBA1 (0.53) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL6235119 | 0.53 | GBA1 (0.53) | ABL1RIN1TDP1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |