Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23731049 | 0.78 | ABL1 (0.32) | GAAABL1RIN1TDP1 | |
| SCHEMBL21389537 | 0.76 | ABL1 (0.35) | GAAALDH1A1ABL1RIN1TDP1 | |
| SCHEMBL21389532 | 0.74 | ABL1 (0.33) | GAAMEN1KMT2AABL1RIN1 | |
| SCHEMBL19505553 | 0.72 | — | — | |
| SCHEMBL837200 | 0.64 | ADORA2B (0.45) | ALDH1A1HTTMEN1KMT2AUSP2 | |
| SCHEMBL835360 | 0.64 | TSHR (0.52) | ALDH1A1HTTMEN1KMT2AHSD17B10 | |
| SCHEMBL14618786 | 0.63 | CYP3A4 (0.35) | KMT2AUSP2CYP1A2TDP1PDE4A | |
| SCHEMBL13247924 | 0.63 | CYP1A2 (0.58) | ALDH1A1HTTMEN1KMT2AUSP2 | |
| SCHEMBL836842 | 0.62 | CYP1A2 (0.53) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17993315 | 0.62 | CYP1A2 (0.67) | ALDH1A1HTTUSP2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3251675-B1 | PREVENTION OR TREATMENT OF URIC ACID OR GOUT DISEASE | SHANTON PHARMA PTE LTD (SG) | 2021-04-21 | — | — | EP | disclosed |