Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389537 | 0.89 | ABL1 (0.35) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL23255225 | 0.74 | GAA (0.33) | ABL1RIN1TDP1GAAMEN1 | |
| SCHEMBL23731049 | 0.72 | ABL1 (0.32) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL18466242 | 0.65 | GBA1 (0.38) | ABL1RIN1TDP1GAAGBA1 | |
| SCHEMBL21389575 | 0.65 | GAA (0.41) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL19066314 | 0.61 | MEN1 (0.65) | TDP1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11371116 | 0.57 | GBA1 (0.58) | ABL1RIN1TDP1GAATP53 | |
| SCHEMBL22570380 | 0.55 | AGTR1 (0.40) | — | |
| SCHEMBL24732505 | 0.55 | AGTR1 (0.40) | — | |
| SCHEMBL19399936 | 0.55 | PDE5A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292186-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292186-A1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | BET1, BRD4, BRD3 | ABL1 2195/4885RIN1 3084/4885TDP1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.