Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984749 | 0.79 | PDK1 (0.39) | HAVCR2PARP1PARP15PARP3 | |
| SCHEMBL21888964 | 0.79 | PDK1 (0.39) | HAVCR2PARP1PARP15PARP3 | |
| SCHEMBL23732125 | 0.73 | HAVCR2 (0.36) | HAVCR2 | |
| SCHEMBL5851446 | 0.68 | PDK1 (0.35) | HAVCR2PARP1PARP15PARP3 | |
| SCHEMBL2756447 | 0.67 | — | — | |
| SCHEMBL24965674 | 0.67 | MAPT (0.43) | NR2E1HTR1BHTR1D | |
| SCHEMBL21889219 | 0.66 | ENPP2 (0.31) | — | |
| SCHEMBL17128162 | 0.66 | HAVCR2 (0.47) | HAVCR2PARP1PARP15PARP3 | |
| SCHEMBL10281378 | 0.66 | HAVCR2 (0.47) | HAVCR2PARP1PARP15PARP3 | |
| SCHEMBL21889260 | 0.65 | ENPP2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155264-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |