Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732167 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23732217 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23732220 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23732168 | 0.79 | KMT2A (0.45) | KDM4ELMNAKMT2AKDM4CMEN1 | |
| SCHEMBL9204471 | 0.75 | CYP19A1 (0.51) | SMN1; SMN2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL23732173 | 0.74 | KMT2A (0.49) | KDM4ELMNAKMT2AKDM4CMEN1 | |
| SCHEMBL1127080 | 0.74 | TSHR (0.55) | SMN1; SMN2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23732190 | 0.74 | GRIA2 (0.41) | SMN1; SMN2ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL23732218 | 0.70 | KMT2A (0.46) | SMN1; SMN2ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23127817 | 0.70 | KMT2A (0.43) | SMN1; SMN2ALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | SMN1; SMN2 3073/4885ALDH1A1 683/4885KDM4E 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.