Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462419 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL23732187 | 0.77 | TSHR (0.47) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL23127819 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGAALMNA | |
| SCHEMBL7166777 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL24157409 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2GAALMNA | |
| SCHEMBL23732185 | 0.75 | NPSR1 (0.60) | ALDH1A1HPGDSMN1; SMN2GAALMNA | |
| SCHEMBL2213963 | 0.74 | NPSR1 (0.70) | ALDH1A1HPGDSMN1; SMN2GAALMNA | |
| SCHEMBL17341813 | 0.74 | TRPV1 (0.57) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA | |
| SCHEMBL14846535 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGAALMNA | |
| SCHEMBL11890412 | 0.73 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236463-A1 | beta-LACTAMASE INHIBITOR | MGAM, CMBL, MGAM2 | ALDH1A1 683/4885HPGD 1246/4885SMN1; SMN2 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.