Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 5/20 | 0.48 |
| ▸ | SRC | P12931 | 11/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CSK | P41240 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | ABL2 | P42684 | 4/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732436 | 0.86 | BRD4 (0.56) | SRCEGFRKDRCSKBRD4 | |
| SCHEMBL23703119 | 0.80 | IGF1R (0.68) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL30050447 | 0.80 | IGF1R (0.68) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL23703120 | 0.80 | IGF1R (0.68) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL23703163 | 0.80 | IGF1R (0.68) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL30051038 | 0.80 | IGF1R (0.68) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL23703240 | 0.77 | IGF1R (0.57) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL30050475 | 0.77 | IGF1R (0.57) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL23703241 | 0.77 | IGF1R (0.57) | IGF1RFLT3SRCEGFRKDR | |
| SCHEMBL23732775 | 0.76 | EGFR (0.48) | IGF1RSRCEGFRKDRCSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |