Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22265836 | 0.70 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL23733099 | 0.69 | TAAR1 (0.50) | TAAR1EGFRERBB2NR3C1BACE1 | |
| SCHEMBL1371390 | 0.68 | TAAR1 (0.57) | TAAR1EGFRERBB2 | |
| SCHEMBL22266033 | 0.68 | NR3C2 (0.36) | — | |
| SCHEMBL6651489 | 0.67 | TAAR1 (0.42) | TAAR1SIGMAR1 | |
| SCHEMBL22265913 | 0.66 | MCL1 (0.32) | ALDH1A1 | |
| SCHEMBL23703162 | 0.65 | TAAR1 (0.53) | TAAR1EGFRERBB2NR3C1 | |
| SCHEMBL4871516 | 0.65 | TAAR1 (0.53) | TAAR1EGFRERBB2 | |
| SCHEMBL12493473 | 0.65 | TAAR1 (0.58) | TAAR1EGFRERBB2BACE1 | |
| SCHEMBL23732878 | 0.65 | TAAR1 (0.57) | TAAR1EGFRERBB2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |