Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ADK | P55263 | 12/20 | 0.56 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ABL2 | P42684 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441782 | 0.86 | MTOR (0.57) | MTORRAB9AADKHASPINABL1 | |
| SCHEMBL16237288 | 0.85 | SRC (0.59) | MTORRAB9AADKABL1EGFR | |
| SCHEMBL13721084 | 0.83 | MTOR (0.55) | MTORRAB9AADKHASPINABL1 | |
| SCHEMBL1933032 | 0.83 | MTOR (0.55) | MTORRAB9AADKHASPINABL1 | |
| SCHEMBL4659181 | 0.83 | ADK (0.56) | MTORRAB9AADK | |
| SCHEMBL23733113 | 0.83 | ADK (0.56) | MTORRAB9AADK | |
| SCHEMBL24650664 | 0.83 | MTOR (0.54) | MTORRAB9AADKHASPINABL1 | |
| SCHEMBL1940882 | 0.82 | ABL1 (0.64) | MTORRAB9AADKABL1EGFR | |
| SCHEMBL400626 | 0.82 | SRC (0.61) | MTORRAB9AADKABL1EGFR | |
| SCHEMBL29484468 | 0.82 | SRC (0.61) | MTORRAB9AADKABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |