SCHEMBL23733113

SCHEMBL23733113

C[C@H]1C[C@H](n2cc(I)c3c(Cl)ncnc32)C1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADK P55263 19/20 0.56
SLC29A1 Q99808 1/20 0.48
MTOR P42345 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4659181 1.00 ADK (0.56) ADKSLC29A1MTORRAB9A
SCHEMBL4659175 0.86 ADK (0.50) ADKSLC29A1MTORRAB9A
SCHEMBL18044688 0.86 ADK (0.56) ADKSLC29A1MTORRAB9A
SCHEMBL18044602 0.86 ADK (0.56) ADKSLC29A1MTORRAB9A
SCHEMBL16236390 0.85 ADK (0.54) ADKSLC29A1MTORRAB9A
SCHEMBL29484542 0.85 ADK (0.54) ADKSLC29A1MTORRAB9A
SCHEMBL23732927 0.84 ADK (0.55) ADKSLC29A1
SCHEMBL23733085 0.83 MTOR (0.57) ADKMTORRAB9A
SCHEMBL1939761 0.82 ADK (0.52) ADKSLC29A1MTORRAB9A
SCHEMBL401328 0.82 ADK (0.52) ADKSLC29A1MTORRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155004-A1 STRAD-BINDING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-05 WO disclosed