Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188310 | 0.80 | TAAR1 (0.47) | TAAR1MAOBCYP2D6NOS1IDO1 | |
| SCHEMBL4234560 | 0.79 | ALDH1A1 (0.60) | TAAR1MAOBMAOACNR1LMNA | |
| SCHEMBL6882189 | 0.77 | ALDH1A1 (0.57) | TAAR1NOS1IDO1 | |
| SCHEMBL6091566 | 0.77 | TAAR1 (0.60) | TAAR1 | |
| SCHEMBL3397240 | 0.76 | TAAR1 (0.50) | TAAR1MAOBMAOA | |
| SCHEMBL1646500 | 0.75 | TAAR1 (0.63) | TAAR1MAOBMAOAIDO1 | |
| SCHEMBL28763529 | 0.75 | TAAR1 (0.63) | TAAR1MAOBCYP2D6IDO1 | |
| SCHEMBL14852200 | 0.75 | MAOB (0.49) | TAAR1MAOBMAOACNR1IDO1 | |
| SCHEMBL28472470 | 0.75 | GLS (0.47) | TAAR1MAOBCYP2D6RIPK1 | |
| SCHEMBL1010819 | 0.75 | TAAR1 (0.62) | TAAR1CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-14 | — | — | US | disclosed |
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | STRAP, STRA6, PLAUR | TAAR1 4465/4885MAOB 1610/4885MAOA 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.