Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733144 | 0.86 | CA1 (0.57) | CA1CA9 | |
| SCHEMBL23732626 | 0.81 | CA1 (0.52) | CA1CA9 | |
| SCHEMBL23733169 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2NFKB1NFKB2RELAL3MBTL1 | |
| Diphenyl Ethanedioat SCHEMBL43364 | 0.74 | TDP1 (0.54) | L3MBTL1ATMTDP1ALDH1A1MAPT | |
| Diphenyl Ethanedioat SCHEMBL27328178 | 0.72 | TDP1 (0.52) | L3MBTL1ATMTDP1ALDH1A1MAPT | |
| SCHEMBL23733167 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2NFKB1NFKB2RELAL3MBTL1 | |
| Diphenyl Ethanedioat SCHEMBL10797780 | 0.70 | TDP1 (0.50) | SMN1; SMN2L3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL28155258 | 0.68 | TDP1 (0.48) | SMN1; SMN2L3MBTL1ATMTDP1ALDH1A1 | |
| Diphenyl Ethanedioat SCHEMBL27942895 | 0.68 | ELANE (0.53) | L3MBTL1ATMTDP1ALDH1A1MAPT | |
| Diphenyl Ethanedioat SCHEMBL7064482 | 0.67 | TDP1 (0.52) | CA1CA9SMN1; SMN2L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238155-A1 | CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS | PYGL, HMOX2, MB | CA1 356/4885CA9 59/4885SMN1; SMN2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.