Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.75 |
| ▸ | DPP4 | P27487 | 8/20 | 0.75 |
| ▸ | PREP | P48147 | 3/20 | 0.75 |
| ▸ | FAP | Q12884 | 7/20 | 0.72 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.69 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27260175 | 1.00 | DPP9 (0.75) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL30776082 | 0.89 | DPP9 (0.79) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL24728961 | 0.89 | DPP9 (0.79) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL23531732 | 0.89 | DPP9 (0.79) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL30069137 | 0.89 | DPP9 (0.79) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL25518164 | 0.88 | FAP (0.74) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL29162894 | 0.88 | DPP4 (0.73) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL29319358 | 0.87 | DPP9 (0.81) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL23733191 | 0.87 | DPP9 (0.67) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL27369825 | 0.86 | DPP4 (0.65) | DPP9DPP4PREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155292-A1 | FIBROBLAST ACTIVATION PROTEIN (FAP) - TARGETED ANTIFIBROTIC THERAPY | LOW PHILIP STEWART (US) | 2021-08-05 | — | — | WO | disclosed |