Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.81 |
| ▸ | DPP4 | P27487 | 8/20 | 0.81 |
| ▸ | PREP | P48147 | 3/20 | 0.81 |
| ▸ | FAP | Q12884 | 7/20 | 0.77 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.76 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23567893 | 0.91 | DPP9 (0.86) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL15130011 | 0.90 | DPP9 (1.00) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL15130010 | 0.90 | DPP9 (1.00) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL29286011 | 0.89 | DPP9 (0.84) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL30338169 | 0.89 | DPP9 (0.84) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL24729425 | 0.88 | DPP9 (0.79) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL27347166 | 0.88 | DPP9 (0.81) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL24729026 | 0.88 | DPP9 (0.81) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL25518164 | 0.88 | FAP (0.74) | DPP9DPP4PREPFAPDPP8 | |
| SCHEMBL23733190 | 0.87 | DPP9 (0.75) | DPP9DPP4PREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | DPP9 263/4885DPP4 385/4885PREP 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.