Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16297552 | 1.00 | KDM4E (0.48) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL16924565 | 0.91 | KDM4E (0.44) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL21016409 | 0.83 | KDM4E (0.64) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL21015405 | 0.83 | KDM4E (0.64) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL800814 | 0.80 | — | — | |
| SCHEMBL23788919 | 0.79 | KMT2A (0.42) | MAPK1TSHRALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL18478347 | 0.78 | — | — | |
| SCHEMBL6636082 | 0.78 | — | — | |
| SCHEMBL21015242 | 0.77 | KDM4E (0.44) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL21431246 | 0.76 | CHRNB2 (0.32) | CHRNB2CHRNB4CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155267-A2 | MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF | MODERNATX, INC. (US) | 2021-08-05 | — | — | WO | disclosed |