SCHEMBL2373359

SCHEMBL2373359

CCOC(=S)c1ccccc1.S=C(Oc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 3/20 0.40
ELANE P08246 3/20 0.40
POLB P06746 1/20 0.39
HPGD P15428 4/20 0.39
KDM4E B2RXH2 1/20 0.39
HSP90AA1 P07900 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
RAB9A P51151 2/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1641519 0.89 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL9041640 0.89 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL3087539 0.84 ELANE (0.42) MAPTALDH1A1MEN1KMT2AELANE
SCHEMBL7583060 0.84 ELANE (0.42) MAPTALDH1A1MEN1KMT2AELANE
Toluene SCHEMBL27857655 0.83 NPC1 (0.46) MAPTALDH1A1MEN1KMT2ANPC1
O-Xylene SCHEMBL27874332 0.83 ALDH1A1 (0.43) MAPTALDH1A1MEN1KMT2ANPC1
Thiobenzoic Acid SCHEMBL17100047 0.83 ALDH1A1 (0.43) MAPTALDH1A1MEN1KMT2ANPC1
Thiobenzoic Acid SCHEMBL27075762 0.83 ALDH1A1 (0.43) MAPTALDH1A1MEN1KMT2ANPC1
Thiobenzoic Acid SCHEMBL23927737 0.81 CA4 (0.45) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL23731517 0.81 LTA4H (0.56) MAPTALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247504-A Self-reinforced oxidative crosslinking type aqueous acrylic resin dispersoid and preparation method thereof 郑州中科新兴产业技术研究院 2023-12-19 CN claimed
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP claimed
US-9023914-B2 Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-05-05 US claimed
US-20140235744-A1 PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2014-08-21 US claimed
US-20120283351-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-11-08 US claimed
CN-117247504-A Self-reinforced oxidative crosslinking type aqueous acrylic resin dispersoid and preparation method thereof 郑州中科新兴产业技术研究院 2023-12-19 CN disclosed
CN-112831222-B Ink, quantum dot film and quantum dot light emitting diode TCL科技集团股份有限公司 2023-05-02 CN disclosed
US-10858455-B2 Process for the production of water and solvent-free nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2020-12-08 US disclosed
US-20160369014-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2016-12-22 US disclosed
US-9469697-B2 Process for the production of water and solvent-free nitrile rubbers LANXESS DEUTSCHLAND GMBH (DE) 2016-10-18 US disclosed
CN-102498140-B Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH 2015-06-24 CN disclosed
US-9023914-B2 Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-05-05 US disclosed
US-20140235744-A1 PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2014-08-21 US disclosed
US-20130211031-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS LANXESS International S.A. (CH) 2013-08-15 US disclosed
EP-2550301-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS Lanxess Deutschland GmbH (DE) 2013-01-30 EP disclosed
US-20120283351-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-11-08 US disclosed
EP-2368916-B1 Process for the production of water and solvent-free nitrile rubbers LANXESS INT SA (CH) 2012-08-22 EP disclosed
CN-102498140-A Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH 2012-06-13 CN disclosed
WO-2011117194-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2011-09-29 WO disclosed
EP-2368916-A1 Process for the production of water and solvent-free nitrile rubbers LANXESS International SA (CH) 2011-09-28 EP disclosed