⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22482485 | 1.00 | — | — | |
| SCHEMBL25619071 | 0.85 | — | — | |
| SCHEMBL1159371 | 0.85 | — | — | |
| SCHEMBL11957183 | 0.85 | — | — | |
| SCHEMBL12350247 | 0.85 | — | — | |
| SCHEMBL8328265 | 0.85 | — | — | |
| SCHEMBL9873278 | 0.85 | — | — | |
| SCHEMBL9657294 | 0.82 | CCR5 (0.61) | — | |
| SCHEMBL5381064 | 0.78 | — | — | |
| SCHEMBL3308474 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027019-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES INC (US) | 2023-01-26 | — | — | US | disclosed |
| US-11084832-B2 | Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use | GILEAD SCIENCES, INC. (US) | 2021-08-10 | — | — | US | disclosed |