Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609550 | 0.83 | DPP4 (0.47) | DPP4DPP7HSD11B1PDE4B | |
| SCHEMBL12282871 | 0.83 | DPP4 (0.47) | DPP4DPP7HSD11B1PDE4B | |
| SCHEMBL13752388 | 0.77 | DPP4 (0.54) | DPP4DPP7HSD11B1CYP3A4CTSK | |
| SCHEMBL6484170 | 0.73 | CHRNB2 (0.46) | DPP4DPP7PDE4B | |
| SCHEMBL3854429 | 0.73 | CHRNB2 (0.46) | DPP4DPP7PDE4B | |
| SCHEMBL1942044 | 0.73 | CHRNB2 (0.46) | DPP4DPP7PDE4B | |
| SCHEMBL21808048 | 0.73 | DPP4 (0.41) | DPP4DPP7HSD11B1NPC1RAB9A | |
| SCHEMBL4595765 | 0.72 | DPP4 (0.48) | DPP4DPP7HSD11B1MEN1KMT2A | |
| SCHEMBL287966 | 0.72 | GPR119 (0.44) | DPP4PDE4BLIPENPC1RAB9A | |
| SCHEMBL701943 | 0.70 | GAA (0.56) | DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084817-B2 | Farnesoid X receptor agonists and uses thereof | METACRINE, INC. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084817-B2 | Farnesoid X receptor agonists and uses thereof | NR1H4, NR1H2, NR1H3 | DPP4 954/4885DPP7 1036/4885HSD11B1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.