SCHEMBL237351

SCHEMBL237351

CCCCCCCCCCCCCCCC(=O)OCC(CO)OC(CO)COC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 4/20 0.79
PRKCE Q02156 2/20 0.79
PRKCQ Q04759 2/20 0.79
PRKCD Q05655 2/20 0.79
LMNA P02545 2/20 0.70
ALDH1A1 P00352 1/20 0.70
KDM4E B2RXH2 1/20 0.68
DUSP3 P51452 1/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
MAPT P10636 2/20 0.64
MAPK1 P28482 1/20 0.64
DGKA P23743 1/20 0.57
ENPP2 Q13822 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528141 1.00 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL15011314 1.00 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL1924789 1.00 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL6430499 0.98 PRKCA (0.76) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL528434 0.91 PRKCA (0.82) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL23668326 0.88 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL3779835 0.88 PRKCA (0.77) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL8049183 0.88 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL23500683 0.88 PRKCA (0.77) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL2502820 0.88 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3554263-A1 COMPOSITIONS AND METHODS THAT MODULATE DIGESTIBILITY IN A COMPANION ANIMAL Société des Produits Nestlé S.A. (CH) 2019-10-23 EP claimed
WO-2018109664-A1 COMPOSITIONS AND METHODS THAT MODULATE DIGESTIBILITY IN A COMPANION ANIMAL NESTEC SA (CH) 2018-06-21 WO claimed
EP-3554255-A1 COMPOSITIONS AND METHODS THAT MODULATE CHOLESTEROL IN A COMPANION ANIMAL Société des Produits Nestlé S.A. (CH) 2019-10-23 EP disclosed
WO-2018109666-A1 COMPOSITIONS AND METHODS THAT MODULATE CHOLESTEROL IN A COMPANION ANIMAL NESTEC SA (CH) 2018-06-21 WO disclosed
EP-2930512-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2018-01-31 EP disclosed
US-9486481-B2 Method of modulating fatty acid mobilization and oxidation REOXCYN DISCOVERIES GROUP, INC. (US) 2016-11-08 US disclosed
EP-2930512-A2 Biomarkers for fatty liver disease and methods using the same Metabolon Inc. (US) 2015-10-14 EP disclosed
EP-2546649-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2015-02-25 EP disclosed
EP-2788763-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-10-15 EP disclosed
WO-2013086365-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-06-13 WO disclosed
EP-2227689-B1 BIOMARKERS FOR FATTY LIVER DISEASE AND METHODS USING THE SAME METABOLON INC (US) 2012-12-26 EP disclosed
US-20120003158-A1 Biomarkers for Inflammatory Bowel Disease and Methods Using the Same METABOLON, INC. 2012-01-05 US disclosed