SCHEMBL8049183

SCHEMBL8049183

CCCCCCCCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 1.00
PRKCE Q02156 2/20 1.00
PRKCQ Q04759 2/20 1.00
PRKCD Q05655 2/20 1.00
ALDH1A1 P00352 1/20 0.84
LMNA P02545 1/20 0.84
MAPT P10636 1/20 0.77
MAPK1 P28482 1/20 0.77
LPAR3 Q9UBY5 3/20 0.67
LPAR1 Q92633 2/20 0.67
ENPP2 Q13822 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
KDM4E B2RXH2 1/20 0.66
DUSP3 P51452 1/20 0.66
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1004733 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL4176661 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL16431424 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL23992003 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL12171707 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL23668326 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8388177 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8048373 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL2502820 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8384466 1.00 PRKCA (1.00) PRKCAPRKCEPRKCQPRKCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP claimed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP claimed
WO-1996009810-A1 METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-04 WO claimed
US-9062225-B2 Production process for colorant, colorant composition, toner, ink for ink jet recording and color filter KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2015-06-23 US disclosed
US-20130260306-A1 PRODUCTION PROCESS FOR COLORANT, COLORANT COMPOSITION, TONER, INK FOR INK JET RECORDING AND COLOR FILTER KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-10-03 US disclosed
US-20120208119-A1 TONER FOR ELECTROPHOTOGRAPHY AND TONER SET KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-08-16 US disclosed
US-7531280-B2 Toner for developing a latent image and an image forming method employing the same KONICA MINOLTA HOLDINGS, INC. (JP) 2009-05-12 US disclosed
US-20080176161-A1 For developing an electrostatic charge image KONICA MINOLTA HOLDINGS, INC. (JP) 2008-07-24 US disclosed
EP-0995430-A2 Use of diacylolycerols for enhancing the barrier function of the skin Beiersdorf Aktiengesellschaft (DE) 2000-04-26 EP disclosed
EP-0655907-B1 USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES UNIV BOSTON (US) 1999-04-28 EP disclosed
US-5750091-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1998-05-12 US disclosed
US-5700450-A Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-12-23 US disclosed
WO-1996009810-A1 METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-04 WO disclosed
US-5352440-A Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 1994-10-04 US disclosed