Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667578 | 1.00 | HSD11B1 (0.39) | HSD11B1UCHL1MAOAGRM5MAOB | |
| SCHEMBL19679354 | 1.00 | HSD11B1 (0.39) | HSD11B1UCHL1MAOAGRM5MAOB | |
| SCHEMBL20873514 | 0.82 | SMN1; SMN2 (0.37) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL23716523 | 0.82 | SMN1; SMN2 (0.37) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL20873513 | 0.82 | SMN1; SMN2 (0.37) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL19684900 | 0.81 | KCNH2 (0.40) | — | |
| SCHEMBL19667491 | 0.80 | HSD11B1 (0.41) | HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL30207832 | 0.80 | HSD11B1 (0.41) | HSD11B1UCHL1MEN1KMT2A | |
| SCHEMBL19667670 | 0.80 | KLK7 (0.42) | — | |
| SCHEMBL22366355 | 0.78 | UCHL1 (0.42) | HSD11B1UCHL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464249-B1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2021-08-11 | — | — | EP | disclosed |