Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KDM5C | P41229 | 2/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660629 | 0.90 | LMNA (0.63) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL22074237 | 0.89 | SMN1; SMN2 (0.50) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL20374795 | 0.88 | PHF8 (0.68) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL14189780 | 0.80 | KMT2A (0.47) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL4572119 | 0.79 | HDAC2 (0.57) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL93970 | 0.79 | — | — | |
| SCHEMBL2754572 | 0.79 | — | — | |
| SCHEMBL7753090 | 0.78 | LMNA (0.57) | LMNAKDM4EPOLBMCL1ALDH1A1 | |
| SCHEMBL5909180 | 0.78 | LMNA (0.57) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL21695688 | 0.77 | LMNA (0.50) | LMNAKDM4EKDM5CEGLN1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |