SCHEMBL7753090

SCHEMBL7753090

CNC(=O)CCCCC(=O)NC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
HDAC3 O15379 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50
HSP90AA1 P07900 1/20 0.46
FAAH O00519 2/20 0.44
RECQL P46063 1/20 0.44
MCL1 Q07820 1/20 0.43
POLB P06746 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
NAMPT P43490 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
MTNR1A P48039 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6159056 0.97 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL12333287 0.97 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL29315161 0.97 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL5909483 0.97 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL5909431 0.97 HDAC3 (0.55) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL5909180 0.93 LMNA (0.57) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL7782849 0.89 LMNA (0.58) LMNAALDH1A1MEN1KMT2ATSHR
SCHEMBL12581893 0.89 PAOX (0.48) LMNAHDAC3HDAC1HDAC2HDAC8
SCHEMBL806271 0.89
SCHEMBL103082 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
WO-2024072908-A1 COMPOUNDS WITH CLEAVABLE DISULFIDE MOIETIES REINVIGORON THERATECH, INC. (US) 2024-04-04 WO disclosed
US-11701864-B2 Metal/resin composite structure and manufacturing method of metal/resin composite structure MITSUI CHEMICALS, INC. (JP) 2023-07-18 US disclosed
US-11701864-B2 Metal/resin composite structure and manufacturing method of metal/resin composite structure MITSUI CHEMICALS, INC. (JP) 2023-07-18 US disclosed
EP-3157978-B1 STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS SYMO CHEM B V (NL) 2021-08-11 EP disclosed
US-20200254728-A1 METAL/RESIN COMPOSITE STRUCTURE AND MANUFACTURING METHOD OF METAL/RESIN COMPOSITE STRUCTURE MITSUI CHEMICALS, INC. (JP) 2020-08-13 US disclosed
US-10618866-B2 Method for synthesising partially N-hydroxyethylated tertiary 1,6-hexanediamines IFP Energies Nouvelles (FR) 2020-04-14 US disclosed
US-20170210736-A1 PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL TAISHO PHARMACEUTICAL CO., LTD (JP) 2017-07-27 US disclosed
US-9649279-B2 Fortified micronutrient salt formulations MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-05-16 US disclosed
US-9096653-B2 Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2015-08-04 US disclosed
US-9065138-B2 Water soluble binder composition, method of producing the same and electrode for rechargeable battery employing the same SAMSUNG SDI CO., LTD. (KR) 2015-06-23 US disclosed
US-20130273423-A1 WATER SOLUBLE BINDER COMPOSITION, METHOD OF PRODUCING THE SAME AND ELECTRODE FOR RECHARGEABLE BATTERY EMPLOYING THE SAME SAMSUNG SDI CO., LTD. (KR) 2013-10-17 US disclosed
US-20130216570-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA The United States of America, as represented by he Secretary, Department of Health and Human 2013-08-22 US disclosed
US-8444996-B2 Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2013-05-21 US disclosed
US-20110182929-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA NEW YORK UNIVERSITY 2011-07-28 US disclosed
US-7795314-B2 Protective role of semapimod in necrotizing enterocolitis CYTOKINE PHARMASCIENCES, INC. (US) 2010-09-14 US disclosed
US-20070282005-A1 HMGB1 EXPRESSION AND PROTECTIVE ROLE OF SEMAPIMOD IN NEC FERRING BV (NL) 2007-12-06 US disclosed
WO-2001058912-A1 DINUCLEAR GROUP 4 METAL BORON OR ALUMINUM BRIDGE CONTAINING ANSA-COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-08-16 WO disclosed
US-4142029-A Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130216570-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA CD47, NASP, CD69 LMNA 4399/4885HDAC3 3289/4885HDAC1 4595/4885
US-20110182929-A1 MULTICOMPONENT VACCINE FOR MALARIA PROVIDING LONG-LASTING IMMUNE RESPONSES AGAINST PLASMODIA CD47, NASP, CD69 LMNA 4399/4885HDAC3 3289/4885HDAC1 4595/4885
US-20070282005-A1 HMGB1 EXPRESSION AND PROTECTIVE ROLE OF SEMAPIMOD IN NEC HMGB1, HMGB2, BAD LMNA 1732/4885HDAC3 2154/4885HDAC1 1382/4885
US-20170210736-A1 PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL NHERF1, SLC9A3, SLC26A3 LMNA 3991/4885HDAC3 69/4885HDAC1 273/4885
US-10618866-B2 Method for synthesising partially N-hydroxyethylated tertiary 1,6-hexanediamines BHMT2, DNMT1, HNMT LMNA 2195/4885HDAC3 1835/4885HDAC1 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.