Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861290 | 1.00 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL25793510 | 0.90 | CASP2 (0.55) | ADRA1ACASP2FAAHNAAADNM1 | |
| SCHEMBL21695694 | 0.90 | KDM4E (0.68) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL8978061 | 0.89 | CASP2 (0.50) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL811258 | 0.89 | CASP2 (0.50) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13292124 | 0.89 | CASP2 (0.50) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL9925439 | 0.89 | CASP2 (0.50) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13445262 | 0.89 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL16864576 | 0.89 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13508623 | 0.89 | CASP2 (0.50) | KDM4EMAPK1HIF1AADRA1APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157978-B1 | STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS | SYMO CHEM B V (NL) | 2021-08-11 | — | — | EP | disclosed |