Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16864576 | 1.00 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL8373380 | 0.96 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL19400309 | 0.96 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL9787810 | 0.96 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL16303445 | 0.94 | KDM4E (0.62) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL23735520 | 0.92 | CASP2 (0.57) | ADRA1ACASP2FAAHNAAANAMPT | |
| SCHEMBL23735524 | 0.92 | CASP2 (0.57) | ADRA1ACASP2FAAHNAAANAMPT | |
| SCHEMBL23735519 | 0.90 | CASP2 (0.55) | ADRA1ACASP2FAAHNAAANAMPT | |
| SCHEMBL23735430 | 0.90 | CASP2 (0.54) | CASP2FAAHNAAANAMPTDNM1 | |
| SCHEMBL21695694 | 0.90 | KDM4E (0.68) | KDM4EMAPK1HIF1AADRA1APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820805-B2 | Conjugate based systems for controlled insulin delivery | MERCK SHARP & DOHME LLC (US) | 2023-11-21 | — | — | US | disclosed |
| US-7678295-B2 | thermoplastic blends of polyphenylene ethers and polycaprolactam, reinforcing fibers and electroconductive fillers, having tensile strength; used as engine housings having improved appearence; injection molding | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-03-16 | — | — | US | disclosed |
| US-20080090953-A1 | thermoplastic blends of polyphenylene ethers and polycaprolactam, reinforcing fibers and electroconductive fillers, having tensile strength; used as engine housings having improved appearence; injection molding | GENERAL ELECTRIC COMPANY (US) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820805-B2 | Conjugate based systems for controlled insulin delivery | GPR119, INSR, IGF1R | KDM4E 2971/4885MAPK1 4342/4885HIF1A 3652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.