Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187510 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1 | |
| SCHEMBL25009530 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL18198890 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL11140291 | 0.77 | MEN1 (0.41) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14682806 | 0.76 | ACE2 (0.46) | KDM4EALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL14255598 | 0.75 | — | — | |
| SCHEMBL8143727 | 0.74 | KDM4E (0.49) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL11839292 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL11137223 | 0.72 | MAOA (0.53) | — | |
| SCHEMBL515382 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154688-B1 | CROSS-LINKING CATALYST COMPRISING SILOXANE STRUCTURAL UNITS | SIKA TECH AG (CH) | 2021-08-11 | — | — | EP | disclosed |