Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140291 | 0.92 | MEN1 (0.41) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL17424836 | 0.88 | TSHR (0.43) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL14255598 | 0.87 | — | — | |
| SCHEMBL18198890 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2CYP2D6TOP2A | |
| SCHEMBL11839292 | 0.82 | KDM4E (0.39) | KDM4EALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL11121197 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL23735548 | 0.80 | KDM4E (0.42) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL515382 | 0.78 | — | — | |
| SCHEMBL23902086 | 0.78 | MEN1 (0.39) | KMT2AMEN1TSHRHTTCYP1A2 | |
| SCHEMBL10076591 | 0.78 | MEN1 (0.39) | KMT2AMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010200-A1 | THERAPEUTIC COORDINATION POLYMERS CONTAINING PHARMACEUTICALS FOR DRUG RELEASE APPLICATIONS | UNIVERSITY OF WINDSOR (CA) | 2023-02-09 | — | — | WO | disclosed |