SCHEMBL29957650

SCHEMBL29957650

CC(C)N(CCC#N)CCC=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.30
NLRP3 Q96P20 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319284 0.83 TSHR (0.40) ALDH1A1TSHRNLRP3
SCHEMBL21532631 0.83 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL2562308 0.82 TSHR (0.31) ALDH1A1TSHRNLRP3
SCHEMBL29955267 0.75 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL13601936 0.75 TSHR (0.44) ALDH1A1TSHRNLRP3
SCHEMBL23735583 0.74 MAPK1 (0.41) ALDH1A1TSHRNLRP3
SCHEMBL15331649 0.74 MEN1 (0.33) ALDH1A1
SCHEMBL29954794 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL29956145 0.73 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL11668657 0.73 TSHR (0.40) ALDH1A1TSHRNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed