Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15726434 | 0.84 | PDE4B (0.35) | PDE4BPDE4APDE4CPDE4DMEN1 | |
| SCHEMBL23736377 | 0.77 | — | — | |
| SCHEMBL15727268 | 0.74 | TERF2 (0.30) | ALDH1A1GAA | |
| SCHEMBL23736111 | 0.68 | SLC6A2 (0.32) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL16003117 | 0.68 | SLC6A2 (0.33) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL22275706 | 0.63 | TP53 (0.32) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL17282907 | 0.63 | GAA (0.33) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL14234967 | 0.63 | GAA (0.33) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL14234456 | 0.63 | GAA (0.33) | PDE4BPDE4APDE4CPDE4DTP53 | |
| SCHEMBL806631 | 0.62 | PDE4A (0.33) | PDE4BPDE4APDE4CPDE4DTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |