Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676500 | 0.85 | ALDH1A1 (0.30) | GAAALDH1A1 | |
| SCHEMBL15727275 | 0.84 | ALDH1A1 (0.31) | GAAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL15726434 | 0.82 | PDE4B (0.35) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL15727268 | 0.79 | TERF2 (0.30) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL14234456 | 0.78 | GAA (0.33) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL17282907 | 0.78 | GAA (0.33) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL14234967 | 0.78 | GAA (0.33) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL16003117 | 0.75 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL14235320 | 0.72 | RXRA (0.33) | ALDH1A1MMP1MMP13PDE4APDE4B | |
| SCHEMBL15253760 | 0.72 | RXRA (0.33) | ALDH1A1MMP1MMP13PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |