Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 4/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | COMT | P21964 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416362 | 0.84 | HDAC6 (0.46) | SCN2ATRPV1COMTKDM4ENPC1 | |
| SCHEMBL23736211 | 0.80 | SCN2A (0.70) | SCN2ANPY5RKDM4ENPC1RAB9A | |
| SCHEMBL26202011 | 0.78 | SCN2A (0.55) | SCN2ATRPV1COMTNPY5RGFER | |
| SCHEMBL11371985 | 0.77 | NPY5R (0.55) | SCN2ANPY5RKDM4ENPC1RAB9A | |
| SCHEMBL18731402 | 0.76 | HDAC4 (0.47) | SCN2ANPY5RGFERKDM4ENPC1 | |
| SCHEMBL7700050 | 0.76 | TRPV1 (0.50) | SCN2ATRPV1NPY5RNPC1RAB9A | |
| SCHEMBL23736202 | 0.76 | SCN2A (0.56) | SCN2ANPY5RGFERKDM4ENPC1 | |
| SCHEMBL236656 | 0.75 | SCN2A (0.61) | SCN2ANPY5RSMPD3HDAC4 | |
| SCHEMBL15331905 | 0.75 | COMT (0.57) | SCN2ATRPV1COMTNPY5RGFER | |
| SCHEMBL5833712 | 0.74 | COMT (0.65) | SCN2ATRPV1COMTNPY5RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
| CN-108349904-A | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | 米托布里奇公司 | 2018-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11090289-B2 | Compositions and methods for blocking sodium channels | SCN3A, SCN1B, SCN2B | SCN2A 7/4885TRPV1 99/4885COMT 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.