Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736109 | 0.93 | KMT2A (0.32) | ITGB3ITGAVITGB5KMT2A | |
| SCHEMBL23736270 | 0.83 | KMT2A (0.32) | KMT2A | |
| SCHEMBL23736281 | 0.82 | — | — | |
| SCHEMBL23736093 | 0.82 | CPB2 (0.35) | — | |
| SCHEMBL15727300 | 0.81 | CTSD (0.32) | PPIAKMT2A | |
| SCHEMBL23736283 | 0.78 | KMT2A (0.31) | KMT2A | |
| SCHEMBL15727225 | 0.77 | CTSD (0.32) | KMT2A | |
| SCHEMBL23736280 | 0.76 | KMT2A (0.33) | KMT2A | |
| SCHEMBL15727251 | 0.75 | CTSD (0.33) | KMT2A | |
| SCHEMBL13640163 | 0.70 | KMT2A (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |