Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736092 | 0.96 | CTSD (0.44) | CTSDBACE1ADAM17CPB2GAA | |
| SCHEMBL15727227 | 0.93 | CTSD (0.51) | CTSDBACE1ADAM17CPB2GAA | |
| SCHEMBL15750383 | 0.89 | CTSD (0.51) | CTSDBACE1ADAM17CPB2GAA | |
| SCHEMBL15727261 | 0.89 | CTSD (0.51) | CTSDBACE1ADAM17CPB2GAA | |
| SCHEMBL23736117 | 0.85 | GAA (0.47) | CTSDBACE1CPB2GAANAAA | |
| SCHEMBL23736288 | 0.82 | CTSD (0.39) | CTSDBACE1ADAM17CPB2REN | |
| SCHEMBL23736034 | 0.80 | GAA (0.48) | CTSDBACE1CPB2GAANAAA | |
| SCHEMBL23736230 | 0.79 | GAA (0.50) | CTSDBACE1CPB2GAAREN | |
| SCHEMBL15727316 | 0.75 | CTSD (0.53) | CTSDBACE1GAANAAA | |
| SCHEMBL15727185 | 0.75 | CTSD (0.46) | CTSDBACE1ADAM17KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |