Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736034 | 0.95 | GAA (0.48) | GAACTSDNAAABACE1CPB2 | |
| SCHEMBL23736230 | 0.93 | GAA (0.50) | GAACTSDBACE1CPB2BTK | |
| SCHEMBL15727316 | 0.89 | CTSD (0.53) | GAACTSDNAAABACE1TERF2 | |
| SCHEMBL15750384 | 0.85 | CTSD (0.47) | GAACTSDNAAABACE1TERF2 | |
| SCHEMBL23736353 | 0.85 | CTSD (0.43) | GAACTSDNAAABACE1CPB2 | |
| SCHEMBL15727299 | 0.83 | CTSD (0.53) | GAACTSDBACE1RENTERF2 | |
| SCHEMBL23736276 | 0.82 | GAA (0.49) | GAACTSDBACE1BTKPLG | |
| SCHEMBL15727314 | 0.82 | CTSD (0.55) | GAACTSDBACE1TERF2 | |
| SCHEMBL23736283 | 0.81 | KMT2A (0.31) | — | |
| SCHEMBL23736282 | 0.81 | GAA (0.47) | GAACTSDBACE1PLGNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |