Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IL6ST | P40189 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522276 | 0.88 | NAAA (0.51) | NAAATDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL23866771 | 0.88 | NAAA (0.51) | NAAATDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL23902846 | 0.88 | NAAA (0.51) | NAAATDP1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL23736405 | 0.85 | NAAA (0.42) | NAAASMN1; SMN2FAAHMEN1KMT2A | |
| SCHEMBL16594226 | 0.81 | NAAA (0.60) | NAAATDP1L3MBTL1FAAH | |
| SCHEMBL16594224 | 0.81 | NAAA (0.60) | NAAATDP1L3MBTL1FAAH | |
| SCHEMBL19192764 | 0.81 | NAAA (0.50) | NAAAFAAHIL6ST | |
| SCHEMBL1915643 | 0.80 | NAAA (0.47) | NAAAL3MBTL1FAAHALDH1A1HPGD | |
| SCHEMBL1915646 | 0.80 | NAAA (0.47) | NAAAL3MBTL1FAAHALDH1A1HPGD | |
| SCHEMBL7346791 | 0.80 | NAAA (0.47) | NAAAL3MBTL1FAAHALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3376870-B1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | AERIE PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |